Hormesis, Nootropics and Organic Acids Testing

May 11, 2017

In this dense and technical episode with Dr Tommy Wood, we introduce Hormetea!

Why Hormetea?

We love polyphenols - those magical compounds from plant foods that lend them their bright colours and multiple health benefits. The greens and yellows in tea, the deep orange of turmeric, and purples of berries. Many of these compounds provide some of their benefits by activating the metabolic machinery associated with fasting and autophagy - a process known as hormesis. To get all these great compounds in one place, we went into the kitchen and cooked up a tea - Hormetea. In one serving, you’ll find the best-researched plant polyphenols in doses that have been clinically-proven to reduce inflammation and improve metabolic health, with a touch of pepper to increase bioavailability. We’re sure you’re going to love it!

We will send the first 100 people that leave us a 5-star review on iTunes (video instructions) a 50g sample of Hormetea. Please send your US shipping address to support@nourishbalancethrive.com

About the Hormetea ingredients:

Polyphenols

Seem to be synergistic (i.e. EGCG inhibits the enzymes that metabolise quercetin)
Anthocyanins (and quercetin) from bilberry
Improves glucose tolerance in obese patients (when given with prebiotics)
Improves disease score in UC (including reduced calprotectin)
Reduces oxidative DNA damage
Improves vascular function
Improves gait speed and agility in the elderly
Reduce insulin and glucose responses to carbs
Inhibits MMPs (MS)

Matcha - green tea catechins

May help reduce fat mass (but requires synergism with caffeine, and may be better in caffeine naive)
Improves insulin sensitivity
Improves cognitive function in those with cognitive decline (with L-theanine)
Reduces carbohydrate absorption (like anthocyanins)

Grape seed extract

Improves blood pressure and inflammation and glycaemic control in IR
Reduces oxLDL

Turmeric

1-5% curcumin
Increase bioavailability with pepper
Likely to not reach high systemic levels - use Meriva
BUT 1-2g of turmeric can reduce CRP
Improved working memory when given with carb load
Rest is good for the gut
Indigestion
Increased intestinal ALP and reduced permeability?

Broccoli seeds

Highest content of sulforaphane
Activated by heat (~160F)
Lots of epidemiological studies on cruciferous veggies and cancer and all-cause mortality (another)
But make sure you’re iodine-replete!
Activates Nrf2 and antioxidant defence
BrSp extracts are neuroprotective in rats
Improves insulin resistance in T2DM
Improved behaviour in ASD
Improves 8-OHdG, GGT, and ALT in those with fatty liver

One piece of simple, actionable advice to improve your health and performance, including the reference(s) to back it up.
One item we read or saw in the health and fitness world recently that we would like to give a different perspective on, and why.
One awesome thing that we think you’ll enjoy!

Here’s the outline of this podcast with Tommy Wood, MD, PhD:

[00:00:29] Icelandic Health Symposium. Tommy's talk from last year’s event.

[00:02:25] This year’s event is called Who Wants to Live Forever.

[00:02:41] Maryanne DeMasi was last year’s host, this year it’s Tommy!

[00:02:55] Speakers: Ben Greenfield, Dr Bryan Walsh, Diana Rogers, Dr Dominic D’Agostino, Dr Doug McGuff, Dr Rangan Chatterjee, Dr Satchidananda Panda.

[00:03:49] Speaker dinner.

[00:03:58] Practitioner workshop.

[00:04:59] Mountain biking in Iceland.

[00:05:18] PHAT FIBRE, Wood, Thomas R., and Christopher Kelly. "Insulin, glucose and beta-hydroxybutyrate responses to a medium-chain triglyceride-based sports supplement: A pilot study." Journal of Insulin Resistance 2.1 (2017): 9.

[00:06:46] PFv2 is more ketogenic (C8 oil).

[00:07:01] Some glucose is required even in low-carb athletes.

[00:07:37] Professor Kieran Clarke.

[00:09:06] Testing nutritional supplements.

[00:10:10] Professor Elizabeth Nance.

[00:10:48] Hormetea.

[00:11:14] Hormesis.

[00:11:32] Plant polyphenols.