HIIT & Cortisol, Histamine, Excessive Cardio & Mood, Exogenous Melatonin & Dopamine, Carnivore Diet, Serum Calcium

Jan. 25, 2022

[00:00:21] High Intensity Interval Training (HIIT) and effects on cortisol and histamine.

Resources:

• Diagram

• Mast Cell Activation in Brain Injury, Stress, and Post-traumatic Stress Disorder and Alzheimer’s Disease Pathogenesis

• Histamine H1 and H2 receptors are essential transducers of the integrative exercise training response in humans

[00:02:53] Potential negative effects of excessive exercise on mood changes and irritability.

[00:04:42] Signs that you’re doing too much cardio.

Resources:

• Overtraining Syndrome (OTS) and Relative Energy Deficiency in Sport (RED-S): Shared Pathways, Symptoms and Complexities

[00:06:52] Cardio exercise while trying to build muscle.

[00:10:24] Walking in conjunction with weight training.

[00:11:07] Effectiveness of walking for cardiovascular benefits.

[00:12:39] Intensity of exercise and fat burning.

[00:13:09] High intensity cardio and effects on mood.

[00:15:02] Exogenous melatonin and dopamine levels. Dr. Andrew Huberman’s Podcast: Controlling Your Dopamine for Motivation, Focus, and Satisfaction.

Resources:

• Acute effects of melatonin administration on cardiovascular autonomic regulation in healthy men

• Melatonin reduces dopamine content in the neurointermediate lobe of male Syrian hamsters (entire article on Sci-Hub)

• Dopamine inhibits melatonin release in the mammalian retina: in vitro evidence

• Melatonin: An Underappreciated Player in Retinal Physiology and Pathophysiology

• Melatonin-dopamine interactions: from basic neurochemistry to a clinical setting

[00:21:05] Avoiding histamine in foods (e.g., coconut aminos, fish sauce).

[00:26:58] Long term solutions for managing high histamine.

[00:42:04] Carnivore diet.

[00:44:00] Getting in more calories on AIP and low-histamine diet.

[00:51:58] Factors that affect serum calcium.

[00:53:35] Elevated HbA1C and triglycerides.