Hydrogen Peroxide for Dental Care, Nitrates & Nitrites in Cured Meats, Imodium

Nov. 2, 2021

[00:01:36] Hydrogen peroxide in dental products: a good idea? Example product: Essential Oxygen BR Organic Toothpaste

[00:02:00] Hydrogen peroxide’s effects on oral microbiota previously discussed during Office Hours in on 7/7/21.

[00:05:26] Nitrates in cured and processed meats: bad for you?

[00:06:28] Nitrates and nitrites previously discussed during Office Hours on 3/31/2020.

Resources:

• Dietary Nitrates, Nitrites, and Nitrosamines Intake and the Risk of Gastric Cancer: A Meta-Analysis
• Association between dietary nitrate and nitrite intake and sitespecific cancer risk: evidence from observational studies
• Association Between Nitrite and Nitrate Intake and Risk of Gastric Cancer: A Systematic Review and Meta-Analysis
• Are all nitrosamines concerning? A review of mutagenicity and carcinogenicity data
• Formation and occurrence of nitrosamines in food
• Effect of plant polyphenols and ascorbic acid on lipid oxidation, residual nitrite and N-nitrosamines formation in dry-cured sausage
• Effects of rosemary extract, grape seed extract and green tea polyphenol on the formation of N-nitrosamines and quality of western-style smoked sausage

[00:10:35] Immodium (Loperamide) for diarrhea - is there benefit?

Resources:

• Loperamide: A pharmacological review
• Loperamide: studies on its mechanism of action
• Effect of codeine and loperamide on upper intestinal transit and absorption in normal subjects and patients with postvagotomy diarrhoea
• Effects of loperamide on anal sphincter function in patients complaining of chronic diarrhea with fecal incontinence and urgency
• Inhibitory actions of loperamide on absorptive processes in rat small intestine
• Mechanisms of action of loperamide
• Loperamide has antisecretory activity in the human jejunum in vivo
• Influence of 1,8-dihydroxyanthraquinone and loperamide on the paracellular permeability across colonic mucosa
• Loperamide. Survey of studies on mechanism of its antidiarrheal activity
• Systematic review of loperamide: No proof of antibiotics being superior to loperamide in treatment of mild/moderate travellers’ diarrhoea
• The effects of loperamide, or loperamide plus simethicone, on the distribution of gut water as assessed by MRI in a mannitol model of secretory diarrhoea
• Diarrhea as a Potential Cause and Consequence of Reduced Gut Microbial Diversity Among Undernourished Children in Peru

[00:16:00] Nitrates/Nitrites - further discussion.

[00:21:32] Ride with GPS; Gravel Riding.

[00:28:34] Book: Natural Born Heroes: Mastering the Lost Secrets of Strength and Endurance, by Christopher McDougall.