Nov. 25, 2016
This year in the United States, over 22,000 people will be diagnosed with a primary brain or spinal tumor. Of these, more than 13,000, many of them younger than 21 years old, will die of their disease. New treatment modalities are critical in the battle against cancer.
Dr. Scheck’s expertise includes neuro-oncology. She is a member of the American Association for Cancer Research, Society for Neuro-Oncology, American Association for Cancer Research, American Society for Biochemistry and Molecular Biology, Women in Cancer Research, and the American Association for the Advancement of Science.
[00:00:37] Dr. Jong M Rho.
[00:03:53] Hanahan, Douglas, and Robert A. Weinberg. "Hallmarks of cancer: the next generation." cell 144.5 (2011): 646-674.
[00:05:01] Cancer metabolism: see Tripping Over the Truth: The Return of the Metabolic Theory of Cancer Illuminates a New and Hopeful Path to a Cure.
[00:05:37] Positron emission tomography (PET).
[00:07:21] Adding ketones to a in vitro model.
[00:09:14] Poff, Angela M., et al. "The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer." PloS one 8.6 (2013): e65522.
[00:11:38] 4:1 KetoCal.
[00:13:14] Dr. Cate Shanahan at the Keto Summit.
[00:21:42] Clinical trial diet is as close to 4:1 as possible.
[00:24:09] Ketones of 3mM, glucose of 4mM.
[00:25:59] Adrienne gave a talk in Banff but I couldn’t find it online.
[00:26:23] Trial eligibility.
[00:30:29] Confounding lifestyle factors.
[00:32:58] MRI for tumor metabolism .
[00:34:25] Is there something special about brain tumors that makes them particularly susceptible?
[00:35:48] Edema, angiogenesis, and inflammation.
[00:37:36] Lussier, Danielle M., et al. "Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet." BMC cancer16.1 (2016): 1.
[00:40:14] Gut microbiome.
[00:41:50] Ketone supplementation.
[00:47:54] Effects in cancer patients may be different from in a healthy person.
[00:48:45] Students Supporting Brain Tumor Research.
[00:50:35] MaxLove Project.
[00:52:28] Finding a physician and a dietician.
[00:55:13] Education for dietitians and practitioners.
[00:58:55] Adam Sorenson and father Brad.
© 2019 nourishbalancethrive