Lp(a) & Vitamin C; Bile Acid Malabsorption

Aug. 3, 2021

[00:04:35] Vitamin C to reduce Lp(a) - any evidence? Podcast: Malcolm Kendrick Podcast: A Statin Nation: Damaging Millions in a Brave New Post-health World.

[00:05:11] Malcolm Kendrick blog post: What causes heart disease part XXIV.

Resources:

• Lipoprotein(a): from ancestral benefit to modern pathogen?
• The Reversibility of Atherosclerosis *
• Hypothesis: lipoprotein(a) is a surrogate for ascorbate
• The effect of high-dose ascorbate supplementation on plasma lipoprotein(a) levels in patients with premature coronary heart disease
• Role of Marginal Vitamin C Deficiency in Atherogenesis: In Vivo Models and Clinical Studies

[00:10:05] Bile acid diarrhea (bile acid malabsorption) - what it is, symptoms, diagnosis, causes.

[00:12:29] Bile acid sequesterants/binders - foods and pharmaceuticals.

[00:13:41] Root causes of bile acid malabsorption.

Resources:

• In vitro binding of bile acids by okra, beets, asparagus, eggplant, turnips, green beans, carrots, and cauliflower
• Managing bile acid diarrhoea
• Bile acid diarrhoea: pathophysiology, diagnosis and management
• Current Practice in the Diagnosis of Bile Acid Diarrhea
• Bile acid malabsorption in chronic diarrhea: pathophysiology and treatment
• The pathophysiology of bile acid diarrhoea: differences in the colonic microbiome, metabolome and bile acids
• Methods for diagnosing bile acid malabsorption: a systematic review
• Management of bile acid malabsorption using low-fat dietary interventions: a useful strategy applicable to some patients with diarrhoea-predominant irritable bowel syndrome?
• A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome

[00:16:22] Dosing magnesium.

[00:24:07] Bone injuries and blood flow.